Murine Model for Non-IgE-Mediated Asthma

IgE- AND NON-IgE MEDIATED FOOD ALLERGY IN CHILDREN

R. Ciorap, Ecaterina Anisie, Celina Stafie, Dana Elena Mîndru, Anca Hăisan, Evelina Moraru, Monica Ungureanu University of Medicine and Pharmacy “Grigore T. Popa”Iaşi Faculty of Bioengineering 1. Department of Biomedical Science Faculty of Medicine 2. Department of Preventive Medicine and Interdisciplinarity 3. Department of Mother and Child Medicine 4. Department of Medical Specialties (II) “S...

Asthma classification by pathophysiology and IgE-mediated allergic reaction: new concepts for classification of asthma.

Bronchial asthma was classified by the pathophysiology and by the mechanism of onset of the disease. Forty asthmatics who had serum IgE levels lower than 200 IU/ml were evaluated by two classification methods. 1. In asthma classified by a score based on clinical findings and examinations, the characteristics of the findings and examination results were compared among three asthma types, i.e., I...

[Non IgE-mediated cow's milk allergy].

Paediatric non-IgE mediated food allergy: guide for practitioners.

AIM Food avoidance in children is increasingly common due to concerns about allergy. We aim to review the current literature on paediatric non-IgE mediated food allergy including what is known about pathophysiology, diagnosis, management and prognosis of common and severe presentations. Considerations regarding appropriate formula selection are also presented. METHODS Common non-IgE mediated ...

Anti-IgE: beyond asthma

Omalizumab (anti-IgE ab) is a recombinant humanized monoclonal antibody (rhuMAb-E25) developed by immunizing mice with human IgE. Then, a monoclonal antibody was selected that recognizes IgE at the same site as the highaffinity receptor for IgE (FcεRI). Omalizumab is the only Mab to date that has been found to be effective and approved by both the FDA and European Medicines Agency (EMA) for the...